Most people find the easiest and most cost-efficient way to get to Lake Tahoe is to fly in to Reno, and then either rent a car or take a shuttle to Lake Tahoe. The drive from the Reno airport to South Lake Tahoe takes approximately one hour, 15 minutes.
Several airlines fly in to Reno-Tahoe International:
And all the main rental car agencies are available at the airport as well:
There is a shuttle that runs directly from the airport to South Lake Tahoe as well, if you prefer not to rent a car:
If you would like to fly direct, Lake Tahoe does have a (very small) private airport, which is located in South Lake Tahoe: